When it comes to reducing the appearance of wrinkles, Botox® has been the go-to choice for more than 20 years. Yet Xeomin®—a cleaner, more purified option—has started to grow in popularity.
Both Botox and Xeomin work by relaxing the muscles that cause wrinkles, but Xeomin’s unique formulation offers several advantages.
In this blog post, we’ll explain the differences between Botox and Xeomin and why Xeomin might be the right choice for you.
Botox vs. Xeomin: A Side-by-Side Comparison
While both Botox and Xeomin are effective for reducing wrinkles, there are some key differences between the two treatments that can help you decide which is best for you.
Below is a comparison chart of the main features of Botox and Xeomin:
| Feature | Botox | Xeomin |
| FDA Approval Year | 2000 | 2010 |
| Ingredients | Botulinum toxin type A + accessory proteins | Pure Botulinum toxin type A (no additives) |
| Onset of Results | 7-14 days | 3-5 days |
| Duration of Results | 3-4 months | 4-6 months |
| Resistance Risk | Slightly higher risk of antibody resistance | Lower risk of antibody resistance due to lack of additives |
| Storage | Requires refrigeration | Does not require refrigeration |
| Cost | Typically more expensive | Generally up to 43% less expensive |
| Comfort | May feel colder due to refrigeration | Warmer and thinner consistency, potentially more comfortable |
| Best for Treating | Dynamic wrinkles (forehead, crow’s feet, frown lines) | Dynamic wrinkles (forehead, crow’s feet, frown lines) |
| Other Uses | Approved for both cosmetic and medical uses (e.g., migraines, excessive sweating) | Primarily cosmetic but also used for medical conditions like cervical dystonia |
What Is Botox?
Botox is an injection made from the protein Botulinum toxin type A. It also contains other complex proteins, but it does not include harmful bacteria. Instead, it uses a purified form of the protein, making it safe for both medical and cosmetic treatments.
Botox works by temporarily stopping muscles from moving, which helps reduce wrinkles and fine lines. It has been approved for cosmetic use since 2000 and remains a popular choice for those looking to smooth their skin.
What Is Xeomin?
Xeomin (“zeo-min”) is an injection made from double-filtered Botulinum toxin type A with no additives, which is why it’s sometimes called “naked Botox.” Since it doesn’t have extra ingredients, it doesn’t need to be refrigerated.
Approved by the FDA in 2010, Xeomin works just like Botox by temporarily paralyzing muscles to reduce wrinkles.
One benefit of Xeomin is that there’s less chance that your body will develop antibodies against the drug that could make future treatments less effective.
Why You Should Consider Xeomin
There are several reasons to consider Xeomin over Botox.
First, you can see results in just 3-5 days, compared to a couple of weeks with Botox. The effects of Xeomin can last up to 6 months, while Botox usually lasts around 3-4 months.
Since Xeomin is highly purified, there’s a lower risk of an allergic reaction, making it a great option for those who have used Botox for a long time and developed a resistance.
Additionally, Xeomin is often less expensive than Botox (up to 43% less!), and many patients find the injections more comfortable due to its thinner consistency and the fact that it’s not cold.
Xeomin Uses
Xeomin is FDA-approved for treating upper facial lines, such as forehead lines, crow’s feet, and the frown lines between the eyebrows, often called “11 lines.” However, it can be used on other areas of the face as well.
Xeomin, like Botox and Dysport, is best for treating “dynamic wrinkles,” which are caused by muscle movement. For “static wrinkles,” which are caused by a loss of tissue, dermal fillers are a better option.
Xeomin can also be used as a preventative treatment to stop wrinkles before they form.
Xeomin Side Effects to Consider
Xeomin injections are widely considered to be safe but side effects (similar to those seen in Botox patients) can occur.
- Headache
- Redness, bruising, or pain at the injection site
- Muscle weakness
- Eye issues (double/blurred vision, drooping or swelling eyelids, dry eyes)
In rare cases, an allergic reaction may happen. If you experience any side effects, including an allergic reaction, notify your injector immediately to ensure proper care.
Contact Your Ageless Center Professional Today
Both Botox and Xeomin are effective treatments for reducing wrinkles and fine lines, but Xeomin offers a more purified option with several key benefits.
With quicker results, longer-lasting effects, and a lower risk of allergic reactions, Xeomin is a great choice for many patients. Whether you’re new to injectables or looking for an alternative after long-term Botox use, Xeomin provides a safe, comfortable solution.
Ready to discover a more youthful you?
Contact Ageless Center today to schedule your consultation.
